Health Risks of Electromagnetic Radiation from Mobile Phone on Brain of Rats

Abstract

2 Abstract: Tremendous concerns have been raised about the possibility that exposure to the electromagnetic radiation (EMR) from mobile phones could affect people's health. This study was carried out in order to investigate the impact of exposure to the (EMR) of mobile phones. Since recent experimental studies suggest a possible link between mobile phone use and reactive oxygen species (ROS) in EM R-induced oxidative damage in tissues. In this study, rats were divided into three groups, The first group was used as control group and the other Two groups were exposed to 900 MHz EMR from mobile phone for one week (1 h/day) and for two weeks (1 h/day). Control group was prepared by turning off the mobile phone while the animals were in the same exposure conditions (sham exposed to EMR). Subsequently, oxidative stress markers and pathological changes in brain tissue were examined for all groups. The results indicated significant increase in plasma lipid peroxide (PLPO) and malondialdehyde (MDA) levels. Also there was significant decrease in brain superoxide dismutase (SOD), catalase (CAT), glutathione reductase (GR) and glutathione peroxidase (GSH-Px) activities in brain tissue. These alterations were indicative for oxidative damage and disturbance in antioxidant system. Histopathological studies revealed cellular injury in brain tissue induced by mobile phone EMR exposure. In conclusion reactive oxygen species may play a role in the mechanism that has been proposed to explain the biological side effects of mobile phone (MP) in brain tissue.