EVALUATION OF ANALGESIC AND ANTI-INFLAMMATORY POTENTIAL OF MIMOSA PUDICA LINN

Abstract

The aim of this work to evaluate the acute toxicity, Analgesic and Anti-Inflammatory activity of Ethanolic extract of Mimosa Pudica Linn . In the acute toxicity study, the extracts were administered in doses of 5, 50, 300 and 2000 mg/kg p.o. and behavioral changes were observed after 24 hrs. In hot plate test the pethidine treated group, Tail flick Diclofenace treated group, and group given ethanolic extracts as 250 mg/kg and 500 mg/kg showed increase in latency time dose dependent manner. Oral administration of ethanolic extract at a dose of 500 mg/kg showed significantly reduction of writhing response induced by acetic acid as compared the dose given at 250 mg/kg.