Concepedia

Hic-5 deficiency attenuates the activation of hepatic stellate cells and liver fibrosis through upregulation of Smad7 in mice

Xiao‐Feng Lei, Wenguang Fu, Joo‐ri Kim‐Kaneyama, Tomokatsu Omoto, Takuro Miyazaki, Bo Li, Akira Miyazaki

Journal of Hepatology · 2015 · 68 citations · 30 references

DOI

Concepts

References

30

Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling

Atsuhito Nakao, Mozhgan Afrakhte, Anita Morn et al. · Nature · 1997 · 1.8K citations

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Liver fibrosis

Ramón Bataller · Journal of Clinical Investigation · 2005 · 1.5K citations · Full text

, , +17

Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology

Ingmar Mederacke, Christine Hsu, Juliane S. Troeger et al. · Nature Communications · 2013 · 1.4K citations · Full text

, , +12

NADPH oxidase signal transduces angiotensin II in hepatic stellate cells and is critical in hepatic fibrosis

Ramón Bataller, Robert F. Schwabe, You-kyung Choi et al. · Journal of Clinical Investigation · 2003 · 546 citations · Full text

, , +17

Angiotensin II induces contraction and proliferation of human hepatic stellate cells

Ramón Bataller, Pere Ginès, Josep M. Nicolás et al. · Gastroenterology · 2000 · 495 citations · Full text

, , +13