Concepedia
PubMed · 2010 · 23 citations · 19 references
This weekly paclitaxel regimen with intermittent IM is tolerable with anti-tumor activity, making it suitable as part of future studies.
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New Guidelines to Evaluate the Response to Treatment in Solid Tumors
Patrick Therasse, Susan G. Arbuck, Elizabeth A. Eisenhauer et al. · JNCI Journal of the National Cancer Institute · 2000 · 15.7K citations
World Health Organization, Solid Tumors, Cancer Management +17
Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations.
Mary Ann Jordan, Robert Toso, Douglas Thrower et al. · Proceedings of the National Academy of Sciences · 1993 · 1.1K citations · Full text
Nm Taxol, Cell Death, Cell Culture +17
Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death.
M A Jordan, K Wendell, Sheila M. Gardiner et al. · PubMed · 1996 · 783 citations
Apoptosis, Cell Death, Cell Proliferation +20
Dose-dense paclitaxel once a week in combination with carboplatin every 3 weeks for advanced ovarian cancer: a phase 3, open-label, randomised controlled trial
Noriyuki Katsumata, Makoto Yasuda, Fumiaki Takahashi et al. · The Lancet · 2009 · 731 citations
Advanced Ovarian Cancer, Medicine, Metronomic Therapy +9
Nonlinear pharmacokinetics and metabolism of paclitaxel and its pharmacokinetic/pharmacodynamic relationships in humans.
Luca Gianni, Christine M. Kearns, Antonio Giani et al. · Journal of Clinical Oncology · 1995 · 559 citations