Concepedia

Gamma Irradiation and Ethylene Oxide in the Sterilization of Native Reindeer Bone Morphogenetic Protein Extract

Tarmo Pekkarinen, Oili A. Hietala, Timo Jämsä, P. Jalovaara

Scandinavian Journal of Surgery · 2005 · 27 citations · 19 references

DOI

Abstract

Native reindeer BMP extract is more sensitive to the effects of ethylene oxide gas sterilization than gamma irradiation. These results suggest that gamma irradiation is recommendable for the sterilization of BMP extracts.

References

19

Preclinical and Clinical Evaluation of Osteogenic Protein-1 (BMP-7) in Bony Sites

S. D. Cook, Samantha L. Salkeld, Laura P. Patron et al. · Humana Press eBooks · 2000 · 144 citations

, , +21

Effect of sterilization on osteoinduction Comparison of five methods in demineralized rat bone

Everard Munting, Jean-Francois Wilmart, Adrien Wijne et al. · Acta Orthopaedica Scandinavica · 1988 · 143 citations

Effect of sterilization on bone morphogenetic protein

Shinichiro Ijiri, Takao Yamamuro, Takashi Nakamura et al. · Journal of Orthopaedic Research® · 1994 · 93 citations

, , +14

Long-Term Evaluation of Bone Formation by Osteogenic Protein 1 in the Baboon and Relative Efficacy of Bone-Derived Bone Morphogenetic Proteins Delivered by Irradiated Xenogeneic Collagenous Matrices

Ugo Ripamonti, B. Van Den Heever, Jean Crooks et al. · Journal of Bone and Mineral Research · 2000 · 83 citations

, , +16

Dose-dependent reduction of bone inductive properties by ethylene oxide

Per Aspenberg, Evelina Johnsson, K.‐G. Thorngren · Journal of Bone and Joint Surgery - British Volume · 1990 · 69 citations

, , +11