MedicineNeurologyRadiologyDiagnostic ImagingDiagnostic RadiologyNeuroradiologyCopper DeficiencySpinal Cord DisordersSpinal Cord ImagingSpinal Cord PathologySpinal DisordersSpine ImagingCervical Spinal Cord AnatomyCopper Metabolism DisordersRadiographic Progression
Copper deficiency has been associated with a clinical syndrome, myeloneuropathy. Radiographic changes resembling B(12) deficiency in the cervical spinal cord have been described. We present a case of copper deficiency myeloneuropathy, with cervical MR imaging findings resembling B(12) deficiency, which partially reversed following copper supplementation. This is, to our knowledge, the first described case of radiographic improvement with copper supplementation.
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Menkes's kinky hair syndrome. An inherited defect in copper absorption with widespread effects.
David M. Danks, Peter E. Campbell, Brian J. Stevens et al. · PubMed · 1972 · 547 citations
Menkes' Kinky Hair Disease: Further Definition of the Defect in Copper Transport
David M. Danks, Elizabeth J. Cartwright, B. Stevens et al. · Science · 1973 · 218 citations
CNS demyelination associated with copper deficiency and hyperzincemia
Călin I. Prodan, Neil R. Holland, P.J. Wisdom et al. · Neurology · 2002 · 130 citations
Medicine, Neurology, Neuroscience +12