Systemic changes of tryptophan catabolites via the indoleamine-2,3-dioxygenase pathway in primary cervical cancer.

Abstract

PCC is associated with increased systemic levels of quinolinic acid and reduced levels of kynurenic acid. In our study population, the Q/K allowed identification of PCC patients with a high level of accuracy. The prognostic power and relevance of this novel proposed index remains to be elucidated in further larger prospective studies.