Brief Report: Pulmonary Function Tests: High Rate of False‐Negative Results in the Early Detection and Screening of Scleroderma‐Related Interstitial Lung Disease

Yossra A. Suliman, Rucsandra Dobrotă, Dörte Huscher, Thi Dan Linh Nguyen‐Kim, Britta Maurer, Suzana Jordan, Rudolf Speich, Thomas Frauenfelder, Oliver Distler

Arthritis & Rheumatology · 2015 · 215 citations · 11 references

Abstract

The derived evidence-based data reveal a high risk of missing significant SSc-related ILD when relying solely on PFTs. More comprehensive screening algorithms for early detection are warranted. In particular, additional imaging investigations for the early detection of SSc-related ILD should be considered in ACA-negative patients with normal FVC values.

References

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