Superoxide dismutase and myeloperoxidase activities in polymorphonuclear leukocytes in acne vulgaris.

Abstract

Propionibacterium acnes may not play a primary role in the pathogenesis of acne as a bacterium. However, the low activity of SOD in PMN may be responsible for the increased levels of superoxide anion radicals in the epidermis. New anti-acne drugs should include substances with lymphocyte stimulating and anti-oxidative properties.