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Cytoprotective Effects of Arbutin Against Tert-Butyl Hydroperoxid Induced Toxicity in Hep-G2 Cell Line
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2012
Year
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ImmunologyCell DeathPharmacotherapyRedox BiologyToxicological MechanismOxidative StressInflammationToxicologyHepatotoxicityAntioxidant EffectsCytoprotective EffectsRedox SignalingBiochemistryHep-g2 Cell LineReactive Oxygen SpecieExperimental ToxicologyPharmacologyDrug-induced Liver InjuryPotential BenefitsHepg2 CellsMedicine
4 Abstract: Arbutin has antioxidative properties with potential benefits in many diseases. In this study, the cytoprotective and antioxidant effects of arbutin against t-BPH induced oxidative stress in Hep G2 cells were evaluated. HepG2 cells were cultured in 24-well plates (2.5×10 cells in 1 ml RPMI-1640 + 10% FBS+1% Pen. 5