2011 · 10 citations · 0 references
Ulcer DevelopmentMedicinal ChemistryAllergyMedicineHerbal MedicineUlcer IndexAntiulcer ActivityPhytopharmacologyToxicologyPhytochemicalAntiulcer ActivitiesDermatologyPhytochemistryPharmacologyDrug Analysis
2 Abstract: The study aimed to investigate the antiulcer effects of the hydroalcoholic and aqueous extracts of bark of Caesalpinia pulcherrima Linn. for antiulcer activities. 200 (CP1)and 400 (CP2)mg/kg b.wt &(CPA) 300 mg/kg b.wt.of the hydroalcoholic and aqueous extracts of Caesalpinia pulcherrima L respectively were evaluated by pylorus ligation models for protection againstAspirin induced ulcer method.. volume of the gastric content, pH were investigated & After centrifugation, acidity is determined by titration with 0.01 N NaOH. Ulcer Index & % of protection were calculated. The CP and CPA. significantly controlled (P<0.001) the Aspirin induced ulcer development. At 200(CP1)and (CPA)300mg/kg both the doses by decreasing the ulcer score in both the ulcer models, It is concluded that the hydro alcoholic and aqueous extracts of bark of Caesalpinia pulcherrima L. can be used as antiulcer herbal medicine.