Influence of Peritoneal Transport Rate, Inflammation, and Fluid Removal on Nutritional Status and Clinical Outcome in Prevalent Peritoneal Dialysis Patients

Abstract

This study shows that, in a selected group of prevalent PD patients assessed after more than 6 months of PD therapy, (1) inflammation was an independent predictor for mortality; (2) reduced TFR was associated with impaired nutritional status, decreased small solute clearance, and inflammation; and (3) peritoneal transport status was not significantly associated with nutritional status and was not associated with subsequent patient survival. These results indicate that a high peritoneal solute transport rate, as such, should not be regarded as a relative contraindication for PD. Instead, the results suggest that more attention should be given to inflammation and inadequate fluid removal as predictors of mortality in PD patients.