2011 · 14 citations · 1 references
MedicineMicrobiologyPharmacologyAntimicrobial PharmacologyAntimicrobial ResistanceStructure-activity RelationshipsAntibacterial AgentsAntibacterial PharmacologyMedicinal PlantsActive Compound IsolationAntimicrobial Compound ScreeningAntimicrobial Natural ProductsBioactivity ScreeningDrug-resistant PathogensMangrove EcosystemsMangrove MicrobiologyMinimum Inhibitory Concentration Determination
2 Abstract: The present study investigated the antibacterial activity of leaves and bark extracts of Ceriops tagal and Pemphis acidula using acetone, methanol, ethanol and water extract against human pathogens such as Pseudomonas aeruginosa, Klebsiella pneumonia, Vibrio parahaemolyticus, Staphylococcus aureus and Vibrio cholera. The Pempis acidula possessed higher antibacterial potency than the Ceriops tagal, with which the highest activity was recorded in methanol extract of bark, more active against S. aureus (17.2 ± 0.1 mm). The minimum inhibitory concentration (MIC) value was obtained as 75 mg/mL for methanol extract of the same. The present preliminary results suggest a baseline idea for further isolation, identification, separation and characterization of active principle compound(s) from the effective mangrove plant, which might be useful for the controlling the drug resistant bacterial pathogens.
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