SPERMATOGENIC ACTIVITY OF ALOE VERA IN ADULT MALE RATS

Abstract

Summary Infertility affects 15% of couples around the world. Male factor accounts for 40+50% of conjugal infertility. Aloe vera is a medicinal plant used to treat several diseases. The purpose of this study was to investigate effects of Aloe vera extract on rat spermatogenesis with emphasis on sperm parameters and hormonal assay. Aloe vera leaf pulp extract, gel extract, and a mixture of both administered to three groups of 10+week old male Wistar rats for 56 consecutive days. Then sperm analysis and hormonal assay were carried out. Results indicated that in all groups except control group the weights of the testes have increased. Epididymal sperm counts and sperm motility have been increased significantly compared to control groups. Analysis of testosterone level between groups showed that the level of this hormone in the groups that treated with Aloe vera has increased remarkably. According to the results of this study, Aloe vera has strong spermatogenic activity by increasing sperm parameters.This study strongly proposes that Aloe vera specially its gel fortifies spermatogenesis and can be a good candidate for manufacturing fertility drugs.