BIOSYNTHESIS, CHARACTERISATION & ANTIFUNGAL ACTIVITY OF SILVER NANOPARTICLES SYNTHESIZED BY THE FUNGUS ASPERGILLUS FOETIDUS MTCC8876

Abstract

The silver nanoparticles synthesized biologically have been widely used in medicinal field. The synthesis of silver nanoparticles has been carried out by using the extracellular filtrate of the fungal strain, Aspergillus foetidus MTCC8876. The synthesis of silver nanoparticles was identified primarily by changing the color of the extracellular filtrate and confirmed with the help of the study of UV-Vis spectroscopy. The synthesized nano particles have further been characterized by the Biophysical techniques like Dynamic light scattering (DLS), Fourier transformation infrared (FTIR), Atomic force microscopy (AFM) and the Transmission electron microscopy (TEM) with studies of Energy dispersive X-ray (EDX) and it was confirmed that the silver nano particles were constituted extracellularly by an extracellular reductase like enzyme, available in the cell- filtrate separated from the biomass, mycelia of Aspergillus foetidus. The results obtained from the study of antifungal activities of the silver nanoparticles are very significant and indicate that the synthesized silver nanoparticles may have an important advantage over conventional antifungal antibiotics.