Expression of Aquaporin-1 in the Peritoneal Tissues: Localization and Regulation by Hyperosmolality

Abstract

AQP1 is widely distributed in the peritoneal cavity and may provide the major aqueous pathway across the peritoneal barrier. In addition, our findings suggested that hyperosmolality increases AQP1-dependent water permeability in peritoneal tissues by regulatIng the translocation and synthesis of AQP1 protein.