Hypertension: Pathophysiology and Treatment

Abstract

Hypertension is a significant risk factor for heart disease, stroke and other cardiovascular diseases and an estimated 970 million people worldwide suffer from the disease resulting in significant morbidity, mortality and financial burden globally. Despite significant advances in pharmaceutical treatment only 53% achieve targeted blood pressure goals largely due to poor patient compliance compelling a structured and flexible yet, individually tailored approach for treatment of HTN.1, 2This review addresses the pathophysiology, diagnosis and current management for the disease.