PubMed · 1999 · 21 citations · 2 references
Life SciencesInfectious DiseasesMicrobiologyMedical MicrobiologyMicrobial PathogenesisSepsisBacterial InfectionsDiagnostic BacteriologyAbscess CultureNeck AbscessesSplenic Abscess
BACKGROUND: Melioidosis, the disease caused by Burkholderia pseudomallei, is common in Southeast Asia. It has also been reported from India, where some investigators feel it is under-diagnosed and under-reported. We report our experience with melioidosis presenting as abscesses at unusual sites. METHODS: All consecutive patients with culture proven B. pseudomallei, who presented to a single surgical unit between 1995 and 1998, were evaluated. RESULTS: Three patients presented with splenic abscesses and one with a soft tissue abscess in the neck. One patient developed septicaemia. All patients responded favourably to ceftazidime and/or co-trimoxazole which was started as soon as the diagnosis was confirmed. CONCLUSION: Melioidosis is under-diagnosed in India, probably due to a low index of suspicion of this disease among clinicians. It should be considered as a possibility when abscesses are encountered at unusual sites. The pus must then be cultured to identify the causative agent.
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Principles and Practice of Infectious Diseases.
Annals of Internal Medicine · 1991 · 12.1K citations
Melioidosis In India: the tip of the iceberg?
T. Jacob John, M V Jesudason, M. K. Lalitha et al. · PubMed · 1996 · 74 citations