Concepedia

Proton-Pump Inhibitors Are Associated With Increased Cardiovascular Risk Independent of Clopidogrel Use

Mette Charlot, Ole Ahlehoff, Mette Lykke Norgaard, Casper H. Jørgensen, Rikke Sørensen, Steen Z. Abildstrøm, Peter Riis Hansen, Jan Kyst Madsen, Lars Køber, Christian Torp‐Pedersen,

Annals of Internal Medicine · 2010 · 12 citations · 20 references

Concepts

Abstract

Based on administrative data from all hospitals in Denmark, this observational study examined the risk for adverse cardiovascular outcomes related to concomitant use of proton-pump inhibitors (PPIs...

References

20

Effects of Clopidogrel in Addition to Aspirin in Patients with Acute Coronary Syndromes without ST-Segment Elevation

New England Journal of Medicine · 2001 · 6.5K citations · Full text

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Early and Sustained Dual Oral Antiplatelet Therapy Following Percutaneous Coronary Intervention

Steven R. Steinhubl, Peter B. Berger, J. Tift Mann et al. · JAMA · 2002 · 3.1K citations

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Influence of Omeprazole on the Antiplatelet Action of Clopidogrel Associated With Aspirin

Martine Gilard, Jean‐Christophe Cornily, Grégoire Le Gal et al. · Journal of the American College of Cardiology · 2008 · 1K citations

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Risk of Adverse Outcomes Associated With Concomitant Use of Clopidogrel and Proton Pump Inhibitors Following Acute Coronary Syndrome

P. Michael Ho · JAMA · 2009 · 1K citations

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Cytochrome P450 2C19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects

Jean‐Sébastien Hulot · Blood · 2006 · 929 citations · Full text

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