Three-Year Duration of Immunity for Canine Distemper, Adenovirus, and Parvovirus After Vaccination with a Multivalent Canine Vaccine

Abstract

A study was conducted to evaluate the 3year duration of immunity claim for the canine distemper virus, canine adenovirus type 2, and canine parvovirus fractions in a commercially available modified-live virus vaccine (Duramune Adult, Fort Dodge Animal Health) that was specially formulated to provide a longer duration of immunity than currently available products that are labeled for 1 year of protection. Vaccinated puppies were protected against the virulent challenge with virus exposures 3 years after vaccination and had fewer clinical signs, lower body temperatures, and greater weight gains compared with nonvaccinated controls.