2013 · 20 citations · 3 references
PharmacyPharmaceuticsPharmacologyDrug DeliveryNanoparticle Drug DeliveryOral Drug DeliveryControlled Release MechanismsDrug EncapsulationLipid-based Drug Delivery SystemsNanocarriers For TherapeuticsNanomedicineNanoparticle Delivery SystemsDrug Delivery NanocarriersLipid Bilayer ArchitectureLipid Bilayer MembranesLipid Bilayer OrganizationLipid NanocarriersLipid-based Drug CarriersLocal Drug DeliveryNanoparticle Drug Delivery Systems
Nanocochleates are novel drug delivery system based upon entrapment of desired drug molecule into the multilayered structure containing solid-lipid bilayer in the form of sheet rolled up in spiral shape. The nanocochleate structure provides protection to encapsulated molecule form surrounding harsh environment. Also it has potential to carry both the hydrophilic & lipophilic drug molecule as it is contains both the forms on its surface & its structure. Nanocochleates can be prepared by many methods & can be used to deliver many active agents for many applications. Nanocochleates is having very less limitations than that of other dosage forms & system & hence, it becomes widely applicable & more potential drug delivery system.
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Cochleates: New Lipid-Based Drug Delivery System
Leila Zarif, John R. Graybill, David S. Perlin et al. · Journal of Liposome Research · 2000 · 82 citations