The TGFbeta1 gene codon 10 polymorphism contributes to the genetic predisposition to high myopia.

Abstract

The frequency of the CC homozygote in the high myopia group was much higher than in the control group, indicating people with the CC homozygote may be at a higher risk of developing high myopia. Varied expression of this gene may contribute to the genetic predisposition to high myopia in Chinese Taiwanese.