Journal of Bone and Joint Surgery - British Volume · 1987 · 36 citations · 15 references
MedicineOrthopaedic SurgeryOrthopedic SurgeryBone ScintigraphyDiagnostic ImagingDiagnostic RadiologyFracture DetectionRadiographic AssessmentFracture HealingImaging SensitivityRadionuclide Bone ImagingRadionuclide Bone ScintigraphyRadionuclide Uptake QuantificationTc-99m Bone ScintigraphyTc-99m Methylene Diphosphonate ImagingTibia Fractures
The uptake of 99mTc-MDP was studied in 73 patients after a tibial fracture. The image obtained five minutes after injection during a period between one and four weeks after fracture was found to be related to the incidence of non-union after six months. A ratio of 1.3 between the uptake at the fracture site and at normal bone adjacent to it predicted non-union in an individual patient with a sensitivity of about 70% and a specificity of 90%.
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