Guidelines for the publication of articles related to platelet concentrates (Platelet-Rich Plasma - PRP, or Platelet-Rich Fibrin - PRF): the international classification of the POSEIDO

Abstract

Platelet concentrates for surgical use are autogenous regenerative preparations, produced by the centrifugation of the patient own blood sample. Most techniques are often regrouped inappropriately under the historical term of Platelet-Rich Plasma (PRP). Since 15 years, their use dramatically increased in many surgical fields, particularly in oral and maxillofacial surgery. The literature on this topic is considerable, but the published results are often contradictory. It is very difficult to sort and interpret the available data, due to a large number of preparation techniques, terminologies and forms of these materials, and the endless list of potential applications. This consensus conference of the Periodontology, Oral Surgery, Esthetic and Implant Dentistry Organization (POSEIDO) was established to support a classification system of these products, in order to improve and clarify the publications on this topic. Four main families of preparations can be defined, depending on their cell content and fibrin architecture: Pure Platelet-Rich Plasma (P-PRP), such as cell separator PRP, Vivostat PRF, PRGF-Endoret or E-PRP; Leukocyte- and Platelet-Rich Plasma (L-PRP), such as Curasan, Regen, Plateltex, SmartPReP, PCCS, Magellan or GPS PRP; Pure Plaletet-Rich Fibrin (P-PRF), such as Fibrinet; and Leukocyte- and Platelet-Rich Fibrin (L-PRF), such as Titanium-prepared PRF and Intra-Spin L-PRF System. P-PRP and L-PRP exist in an inactivated liquid form, and can be activated and transformed respectively into a P-PRP gel and a L-PRP gel. This terminology will serve as a basis for future works to be published in the POSEIDO journal and as a first step for further research on the topic.