International Journal of Drug Development and Research · 2011 · 26 citations · 40 references
PharmacyChemistryMedicinal ChemistryDrug DesignDrug DiscoveryStructure-activity RelationshipsHeterocyclic ChemistryHeterocyclic CompoundsHit-to-lead OptimizationLead Compound DesignStructure-activity Relationship AnalysisHeterocyclic Medicinal ChemistryMedicinal Chemistry ApplicationsMedicinal HeterocyclesSmall Molecule Drug DesignSmall Molecule Drug DevelopmentThiazole Chemistry
Many compounds bearing five membered heterocyclic rings in their structure have an extensive spectrum of biological activities. The search for new biologically active thiazole analogues continues to be an area of intensive investigation in medicinal chemistry. The present review describes ongoing research in search for new thiazole compounds that can prove useful for the design of future target and development of new drug molecule.
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Bakr F. Abdel‐Wahab, Hatem A. Abdel‐Aziz, Essam M. Ahmed · European Journal of Medicinal Chemistry · 2008 · 222 citations