PubMed · 2012 · 20 citations · 15 references
MedicineCardiologyCardiovascular GeneticsDiabetologyPreventive CardiologyCardiovascular DiseaseCardiovascular EpidemiologyCardiovascular RiskDiabetes MellitusCardiovascular Risk DetectionCardiovascular Risk MarkersEpidemiological MeasurementWaist Circumference Measurement
OBJECTIVE: The current study aimed to investigate the association of wrist circumference with major cardio metabolic risk factors. METHODS: This study was conducted in 2005-2007 among 3000 first-degree relatives of diabetic patients in Isfahan, Iran. RESULTS: Overall, 1709 (386 males and 1323 females) participants were enrolled in this study. The association of wrist circumference with cardio- metabolic risk factors was significantly positive with waist circumference (p = 0.001), BMI (p = 0.001), and LDL-C (p = 0.01), but significantly inverse with HDL-C (p = 0.001). The corresponding figure was not significant for triglycerides (p = 0.13), total cholesterol (p = 0.13), systolic BP (p = 0.15), diastolic BP (p = 0.6), and HbA1c (p = 0.4). CONCLUSION: Measurement of wrist circumference can serve as an easy-to-detect clinical marker to identify individuals at risk of cardio metabolic disorders, and can be used in large epidemiological studies.
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Sarah H. Wild, Gojka Roglić, Anders Green et al. · Diabetes Care · 2004 · 15.3K citations
A genome-wide association study identifies novel risk loci for type 2 diabetes
Robert Sladek, Ghislain Rocheleau, Johan Rung et al. · Nature · 2007 · 3K citations