Structure-Related Inhibition of Calmodulin-Dependent Neuronal Nitric-Oxide Synthase Activity by Melatonin and Synthetic Kynurenines

Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures.

Valina L. Dawson, Ted M. Dawson, Edythe D. London et al. · Proceedings of the National Academy of Sciences · 1991 · 2.2K citations

Life Sciences, Neurobiology, Neuroscience +17

Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum.

David S. Bredt, S H Snyder · Proceedings of the National Academy of Sciences · 1989 · 1.8K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Formation of nitric oxide from L-arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase.

Richard G. Knowles, Richard Palmer, Salvador Moncada · Proceedings of the National Academy of Sciences · 1989 · 1.4K citations · Full text

Life Sciences, Biochemistry, Neurobiology +13

Blood–Brain Barrier Transport of Kynurenines: Implications for Brain Synthesis and Metabolism

Shinsuke Fukui, Robert Schwarcz, Stanley I. Rapoport et al. · Journal of Neurochemistry · 1991 · 761 citations

Medicine, Neuroscience, Pharmacology +17

Nitric oxide synthase regulatory sites. Phosphorylation by cyclic AMP-dependent protein kinase, protein kinase C, and calcium/calmodulin protein kinase; identification of flavin and calmodulin binding sites.

David S. Bredt, C D Ferris, Solomon H. Snyder · Journal of Biological Chemistry · 1992 · 614 citations · Full text

Life Sciences, Biochemistry, Cell Biology +13