Concepedia

Suppression by L-methionine of cell cycle progression in LNCaP and MCF-7 cells but not benign cells.

Maximo A. Benavides, Karen L. Hagen, Wen‐Feng Fang, Pan Du, Simon Lin, Mary Pat Moyer, Wancai Yang, Kirby I. Bland, William E. Grizzle, Maarten C. Bosland

PubMed · 2010 · 10 citations · 19 references

Full text

Open access

Abstract

L-Methionine selectively inhibits proliferation of breast and prostate cancer cells, but not non-tumorigenic cells, and may thus have therapeutic benefits. p53 status appeared to determine the cell cycle stage at which methionine acts.

References

19

Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing

Yoav Benjamini, Yosef Hochberg · Journal of the Royal Statistical Society Series B (Statistical Methodology) · 1995 · 105.5K citations

Engineering, Statistical Foundation, Powerful Approach +21

Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments

Gordon K. Smyth · Statistical Applications in Genetics and Molecular Biology · 2004 · 11.9K citations

Transcriptomics Technology, Empirical Bayes Methods, Linear Models +21

A Human Cell Line From a Pleural Effusion Derived From a Breast Carcinoma 2

Herbert D. Soule, J. Vázquez, Anna Long et al. · JNCI Journal of the National Cancer Institute · 1973 · 2.4K citations

Breast Oncology, Pathology, Pleural Effusion +9

<i>lumi</i>: a pipeline for processing Illumina microarray

Pan Du, Warren A. Kibbe, Simon Lin · Bioinformatics · 2008 · 2K citations · Full text

LNCaP model of human prostatic carcinoma.

Julius S. Horoszewicz, Susan S. Leong, Elzbieta Kawinski et al. · PubMed · 1983 · 1.8K citations

Urology, Developmental Biology, Lncap Cell Line +13