Automated Electrochemical Analyzer as a New Tool for Detection of Thiols

Vojtěch Adam, Ivo Fabrik, Veronika Kohoutková, Petr Babula, Jaromír Hubálek, Libuše Trnková, René Kizek

International Journal of Electrochemical Science · 2010 · 41 citations · 111 references

DOIFull text

Open access

Concepts

Abstract

Stationary electrochemical analysers are advantageous tools for detection of electroactive species. There advantages are low cost, sensitivity and repeatability. However, non-automated injection of samples belongs to their main disadvantages. We aim our attention to present a new electrochemical tool connected with unique autosampler enabling us to inject units of μl, which is essential in for detection of biological samples. The analyser can be used for detection of peptides, proteins, nucleic acids, drugs. Moreover, the highest sensitivity has for thiols. The recent advances in the field of electrochemistry of mentioned biologically active compounds, mainly metallothionein, are also discussed.

References

111