5-Fluorouracil Chemotherapy for Dihydropyrimidine Dehydrogenase-deficient Patients: Potential of the Dose-escalation Method.

Yoichiro Yoshida, Kenichiro Ogura, Akira Hiratsuka, Naoya Aisu, Teppei Yamada, Daibo Kojima, Syu Tanimura, Kentaro Ogata, Shuuji Hara, Ai Mogi,

PubMed · 2015 · 19 citations · 0 references

Abstract

This is the first report to indicate that DPD activity can be induced. These findings may provide early indications of a new method for chemotherapy for DPD-deficient patients.