Concepedia

Publication | Open Access

Dextran sulfate triggers platelet aggregation via direct activation of PEAR1

DOIFull Paper Access

22

Citations

12

References

2015

Year

Christophe Vandenbriele, Yi Sun, Maarten Criel, Katrien Cludts, Soetkin Van kerckhoven, Benedetta Izzi, Thomas Vanassche, Peter Verhamme, Marc Hoylaerts
Platelets

Abstract

The DxS-induced aggregation of human and murine platelets is the result of activation of PI3K/Akt through direct PEAR1 phosphorylation and parallel Syk-signaling through CLEC-2.

References

YearCitations

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