Multi-centre, double blind, randomized trial of three steroid regimens in the treatment of type-1 reactions in leprosy

Abstract

The two 20-week regimens were significantly better than the 12-week regimen. The high dose 20-week regimen was marginally and non-significantly better than the low dose regimen, but the high dose regimen contained 50% more steroid. Reactions in leprosy persist over many months and require long courses of steroids.