The pathogenesis of sendai virus infection in the mouse lung (Plates V-VII)

Abstract

Summary Sendai virus replicates well in the lungs of mice, where it produces extensive damage to the mucous membrane, but no obvious clinical illness. Rapid elimination of virus from the lungs commences after the 5th day of the infection and is associated with a mononuclear response, interferon production and antibody formation. The relative significance of these factors in terminating the infection is discussed.