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MICROWAVE-INDUCED ONE-POT SYNTHESIS OF 2,4,5- TRIARYLIMIDAZOLES USING GLYOXYLIC ACID AS A CATALYST UNDER SOLVENT-FREE CONDITIONS

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2008

Year

Abstract

A simple and highly efficient method for a three-component condensation of benzil/benzoin, aldehydes and ammonium acetate under microwave irradiation in the presence of Glyoxylic acid (CHOCOOH) in solventfree condition to afford the corresponding 2,4,5-triarylimidazole derivatives in high yields. The remarkable advantages offered by this method are inexpensive and readily available catalyst, simple procedure, much faster (1-3 min) reactions and high yield of products.