Concepedia

AlCl<sub>3</sub>·6H<sub>2</sub>O/KI/H<sub>2</sub>O/CH<sub>3</sub>CN:  A New Alternate System for Dehydration of Oximes and Amides in Hydrated Media

Monalisa Boruah, Dilip Konwar

The Journal of Organic Chemistry · 2002 · 70 citations · 8 references

DOI

Concepts

Abstract

Dehydration of oximes and amides to nitriles was carried out using the AlCl(3) x 6H(2)O/KI/H(2)O/CH(3)CN system. It produced isoquinoline derivatives 8a-c (Bischler Naperialski reaction) when reacted with amides 7a-c in hydrated media. Also, the keto oximes produced anilides (Beckmann rearrangement) with the system under the same reaction conditions.

References

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