Elevated Serum Levels of Calprotectin (Myeloid-Related Protein 8/14) in Patients with Ankylosing Spondylitis and Its Association with Disease Activity and Quality of Life

Abstract

Our results suggest that calprotectin might play an important role in the pathogenetic mechanisms of AS; however, the calprotectin levels did not correlate with the measurements of disease activity, functional abilities, radiological damage, and the quality of life in these patients. Further insight into this area of research might provide opportunities to develop novel treatment strategies, which take into account the role of these peptides in the pathogenetic mechanisms of AS.