Concepedia

Functional analysis and crystallographic structure of clotrimazole bound OleP, a cytochrome P450 epoxidase from Streptomyces antibioticus involved in oleandomycin biosynthesis

Linda Celeste Montemiglio, Giacomo Parisi, Antonella Scaglione, Giuliano Sciara, C. Savino, Beatrice Vallone

Biochimica et Biophysica Acta (BBA) - General Subjects · 2015 · 28 citations · 36 references

Concepts

MedicineBiochemistryPharmacologyDrug MetabolismEnzymologyStructure-activity RelationshipsCatalytic MechanismsCytochrome P450 EnzymesCytochrome P450-mediated MetabolismDrug-metabolizing EnzymesMicrobial Natural Product BiosynthesisStructure-metabolism RelationshipsCytochrome P450 CatalysisCytochrome P450 Metabolic PathwaysCytochrome P450 PathwaysCytochrome P450 Reaction MechanismsCytochrome P450 Structure-function Relationships

References

36

PROCHECK: a program to check the stereochemical quality of protein structures

Roman A. Laskowski, Malcolm W. MacArthur, D. S. Moss et al. · Journal of Applied Crystallography · 1993 · 24.6K citations

Life Sciences, Biochemistry, Bioinformatics +9

The CCP4 suite: programs for protein crystallography

Number Collaborative Computational Project · Acta Crystallographica Section D Biological Crystallography · 1994 · 17.3K citations

Life Sciences, Biochemistry, Biophysics +15

Wolfgang Kabsch · Acta Crystallographica Section D Biological Crystallography · 2010 · 16.9K citations · Full text

Computing, Computer Science, Computational Geometry +13

Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

Axel T. Brünger · Nature · 1992 · 3.9K citations

Natural Sciences, Chemistry, Physics +16

Dali server: conservation mapping in 3D

Liisa Holm · Nucleic Acids Research · 2010 · 3.7K citations · Full text

Life Sciences, Bioinformatics, Biology +14