Concepedia

A new approach to oligonucleotide labelling using Diels–Alder cycloadditions and detection by SERRS

Ljiljana Fruk, Antonio Grondin, W. Ewen Smith, Duncan Graham

Chemical Communications · 2002 · 41 citations · 12 references

DOI

Concepts

Abstract

Diels-Alder cycloaddition has been used to add a benzotriazole azo dye to a diene tagged oligonucleotide to generate unique SERRS signals at 10 attomoles.

References

12

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Selective Detection of Deoxyribonucleic Acid at Ultralow Concentrations by SERRS

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