Synthesis of novel tricyclic oxazolidinones by a tandem SN2 and SNAr reaction: SAR studies on conformationally constrained analogues of Linezolid

Synthesis and Antibacterial Activity of U-100592 and U-100766, Two Oxazolidinone Antibacterial Agents for the Potential Treatment of Multidrug-Resistant Gram-Positive Bacterial Infections

Steven J. Brickner, Douglas K. Hutchinson, Michael R. Barbachyn et al. · Journal of Medicinal Chemistry · 1996 · 570 citations

Antibacterial Activity, Antimicrobial Chemotherapy, Drug Resistance +16

Multiple-Antibiotic-Resistant Pathogenic Bacteria -- A Report on the Rockefeller University Workshop

Alexander Tomasz · New England Journal of Medicine · 1994 · 425 citations · Full text

Pathogenic Microbiology, Small Group, Antibiotic Resistance +18

Oxazolidinone Antibacterial Agents

Steven J. Brickner · Current Pharmaceutical Design · 1996 · 169 citations

Antibiotics, Biochemistry, Oxazolidinone Antibacterial Agents +13

Antibiotics That Resist Resistance

Robert F. Service · Science · 1995 · 147 citations

Antibiotic Resistance, Drug Resistance, Medicinal Chemistry +19

Synthesis of Conformationally Constrained Analogues of Linezolid:  Structure−Activity Relationship (SAR) Studies on Selected Novel Tricyclic Oxazolidinones

Natesan Selvakumar, Deekonda Srinivas, Manoj Kumar Khera et al. · Journal of Medicinal Chemistry · 2002 · 69 citations

Bioactive Conformation, Medicinal Chemistry, Pharmaceutical Chemistry +15