A simple entry to chiral non-racemic 2-piperazinone derivatives

Peptidomimetics for Receptor Ligands—Discovery, Development, and Medical Perspectives

Athanassios Giannis, Thomas Kolter · Angewandte Chemie International Edition in English · 1993 · 778 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

2,3-Pyrrolidinedicarboxylates as Neurotransmitter Conformer Mimics: Enantioselective Synthesis via Chelation-Controlled Enolate Alkylation

John M. Humphrey, Richard J. Bridges, Jill A. Hart et al. · The Journal of Organic Chemistry · 1994 · 83 citations

Natural Sciences, Chemistry, Medicinal Chemistry +7

Synthesis of chiral piperazin-2-ones as model peptidomimetics

John DiMaio, B. Belleau · Journal of the Chemical Society Perkin Transactions 1 · 1989 · 51 citations

Pharmacy, Chemistry, Medicinal Chemistry +12

Non-peptide glycoprotein IIb/IIIa inhibitors. 6. Design and synthesis of rigid, centrally constrained non-peptide fibrinogen receptor antagonists

Ben Askew, Charles McIntyre, C. A. HUNT et al. · Bioorganic & Medicinal Chemistry Letters · 1995 · 35 citations

Pharmacy, Medicinal Chemistry, Pharmacology +11

Synthesis of chiral non-racemic 3-(dioxopiperazin-2-yl)propionic acid derivatives

Manuela Weigl, Bernhard Wünsch · Tetrahedron · 2002 · 28 citations

Natural Sciences, Chemistry, Medicinal Chemistry +2