The Journal of Organic Chemistry · 2003 · 100 citations · 1 references
Natural SciencesChemistryCatalysisOrganic ChemistryCross-coupling ReactionsHeterocycle SynthesisHeterocyclic ChemistryHeterocyclic CompoundsOrganic SynthesisTarget-oriented SynthesisAsymmetric Heterocycle SynthesisHeterocyclic ReactivityScopeTransition-metal-catalyzed Heterocycle Synthesis
A versatile and high-yielding indium trichloride mediated cyclization reaction of silylated homoallylic alcohols, thiols, or amines with aldehydes or epoxides is described as a rapid route to a range of unsaturated heterocycles. The excellent diastereoselectivity observed offers a method of wide scope and generality.
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