Concepedia

A Novel Histone Deacetylase Inhibitor, AR-42, Reactivates HIV-1 from Chronically and Latently Infected CD4⁺ T-cells

Jesse J. Kwiek, Jessica M. Mates, Suresh de Silva, Mark Lustberg, Kelsey Van Deusen, Robert A. Baiocchi

Retrovirology Research and Treatment · 2015 · 11 citations · 16 references

DOIFull text

Open access

Concepts

Abstract

T-cells.

References

16

Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection

Gilad Doitsh, Nicole Galloway, Xin Geng et al. · Nature · 2013 · 1.2K citations · Full text

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Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

Nancie M. Archin, Abigail Liberty, Angela D. M. Kashuba et al. · Nature · 2012 · 1.2K citations

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HIV reproducibly establishes a latent infection after acute infection of T cells in vitro

Albert Jordan, Dwayne A. Bisgrove, Eric Verdin · The EMBO Journal · 2003 · 959 citations · Full text

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Early establishment of a pool of latently infected, resting CD4 <sup>+</sup> T cells during primary HIV-1 infection

Tae‐Wook Chun, Delphine Engel, M. Michelle Berrey et al. · Proceedings of the National Academy of Sciences · 1998 · 835 citations · Full text

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Tumor necrosis factor alpha induces expression of human immunodeficiency virus in a chronically infected T-cell clone.

T M Folks, Kathleen A. Clouse, J. Shawn Justement et al. · Proceedings of the National Academy of Sciences · 1989 · 718 citations · Full text

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