Involvement of pregnane X receptor in the impaired glucose utilization induced by atorvastatin in hepatocytes

Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial—Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial

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Medicine, Cardiology, Pharmacotherapy +14

MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial

Rory Collins, Jane Armitage, Sarah Parish et al. · The Lancet · 2003 · 2.9K citations

Medicine, Cardiology, Pharmacotherapy +13

Primary prevention of cardiovascular disease with pravastatin in Japan (MEGA Study): a prospective randomised controlled trial

Haruo Nakamura, Kikuo Arakawa, Hiroshige Itakura et al. · The Lancet · 2006 · 961 citations

Medicine, Cardiology, Preventive Medicine +9

Pravastatin and the Development of Diabetes Mellitus

Dilys J. Freeman, John Norrie, Naveed Sattar et al. · Circulation · 2001 · 845 citations · Full text

Medicine, Endocrinology, Internal Medicine +16

Role of NF-κB in Regulation of PXR-mediated Gene Expression

Xinsheng Gu, Sui Ke, Duan Liu et al. · Journal of Biological Chemistry · 2006 · 301 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +13