Two new simple iridoids from the ant-plant <i>Myrmecodia tuberosa</i> and their antimicrobial effects

Nguyen Phuong Hanh, Nguyễn Hữu Toàn Phần, Nguyễn Thị Diệu Thuần, Trần Thị Hồng Hạnh, Le Thi Vien, Nguyễn Phương Thảo, Nguyễn Văn Thành, Nguyễn Xuân Cường, Nguyễn Quốc Bình, Nguyễn Hoài Nam,

Natural Product Research · 2015 · 13 citations · 9 references

Abstract

Six iridoid derivatives (1-6), including two new compounds myrmecodoides A and B (1 and 2), were isolated from the ant-plant Myrmecodia tuberosa. Their structures were determined on the basis of spectroscopic data ((1)H and (13)C NMR, HSQC, HMBC, (1)H-(1)H COSY, NOESY and HR-ESI-MS) and by comparison with the literature values. Among isolates, 3 and 4 exhibit weak antibacterial effect against Staphylococcus aureus subsp. aureus with MIC value of 100.0 μg/mL.

References

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