Combined, independent small molecule release and shape memory via nanogel-coated thiourethane polymer networks

Eric A. Dailing, Devatha P. Nair, Whitney K. Setterberg, Kyle A. Kyburz, Chun Yang, Tyler D’Ovidio, Kristi S. Anseth, Jeffrey W. Stansbury

Polymer Chemistry · 2015 · 18 citations · 37 references

Concepts

Abstract

culturing of human mesenchymal stem cells with SMPs coated with dexamethasone-loaded nanogels. This article offers a new strategy to independently tune multiple functions on a single polymeric device, and has broad application toward implantable, minimally invasive medical devices such as vascular stents and ocular shunts, where local drug release can greatly prolong device function.

References

37