Concepedia

Chelation control associated with organometallic addition reactions in water. The high stereoselectivity offered by α- and β-hydroxyl substituents obviates the need for protecting groups

Leo A. Paquette, Thomas M. Mitzel

Tetrahedron Letters · 1995 · 53 citations · 27 references

DOI

Concepts

References

27

Chelation or Non‐Chelation Control in Addition Reactions of Chiral α‐ and β‐ Alkoxy Carbonyl Compounds [New Synthetic Methods (44)]

Manfred T. Reetz · Angewandte Chemie International Edition in English · 1984 · 686 citations

, , +14

Studies in Stereochemistry. XXX. Models for Steric Control of Asymmetric Induction<sup>1</sup>

Donald J. Cram, Karl R. Kopecky · Journal of the American Chemical Society · 1959 · 506 citations

, , +11

Water-Promoted Organic Reactions

André Lubineau, Jacques Augé, Yves Queneau · Synthesis · 1994 · 438 citations

, , +13

Chelation-controlled nucleophilic additions. 1. A highly effective system for asymmetric induction in the reaction of organometallics with α-alkoxyketones.

W. Clark Still, John H. McDonald · Tetrahedron Letters · 1980 · 309 citations

, , +9

Indium in organic synthesis: indium-mediated allylation of carbonyl compounds

Shuki Araki, Hirokazu Ito, Yasuo Butsugan · The Journal of Organic Chemistry · 1988 · 267 citations

, , +6