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An Asymmetric Synthesis of Both Enantiomers of the Indole Alkaloid Deplancheine
60
Citations
10
References
2004
Year
Asymmetric ApproachEnantioselective SynthesisEngineeringBoth EnantiomersBiochemistryAsymmetric SynthesisOrganic ChemistryStereoselective SynthesisIndole Alkaloid DeplancheinePharmacologyAsymmetric CatalysisSynthetic ChemistryNonracemic Chiral TemplateBiomolecular EngineeringNatural Product Synthesis
We report a novel, facile and asymmetric approach to both enantiomers of the indole alkaloid deplancheine from a readily available, nonracemic chiral template. The natural product and its antipode are isolated with >95% ee.
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