One-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones using chloroacetic acid as catalyst

Dihydropyrimidine calcium channel blockers. 3. 3-Carbamoyl-4-aryl-1,2,3,4-tetrahydro-6-methyl-5-pyrimidinecarboxylic acid esters as orally effective antihypertensive agents

Karnail S. Atwal, Brian N. Swanson, Steven E. Unger et al. · Journal of Medicinal Chemistry · 1991 · 784 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

Calcium Entry Blockers and Activators: Conformational and Structural Determinants of Dihydropyrimidine Calcium Channel Modulators

George C. Rovnyak, S. David Kimball, Barbara Beyer et al. · Journal of Medicinal Chemistry · 1995 · 549 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Lanthanide Triflate Catalyzed Biginelli Reaction. One-Pot Synthesis of Dihydropyrimidinones under Solvent-Free Conditions

Yun Ma, Changtao Qian, Limin Wang et al. · The Journal of Organic Chemistry · 2000 · 518 citations

Natural Sciences, Chemistry, Catalysis +5

Indium(III) Chloride-Catalyzed One-Pot Synthesis of Dihydropyrimidinones by a Three-Component Coupling of 1,3-Dicarbonyl Compounds, Aldehydes, and Urea: An Improved Procedure for the Biginelli Reaction

Brindaban C. Ranu, Alakananda Hajra, Umasish Jana · The Journal of Organic Chemistry · 2000 · 474 citations

Natural Sciences, Chemistry, Catalysis +5

Dihydropyrimidine calcium channel blockers. II. 3-Substituted-4-aryl-1,4-dihydro-6-methyl-5-pyrimidinecarboxylic acid esters as potent mimics of dihydropyridines

Karnail S. Atwal, George C. Rovnyak, S. David Kimball et al. · Journal of Medicinal Chemistry · 1990 · 378 citations

Pharmacy, Medicinal Chemistry, Pharmacology +8