Domino “[3+3]-Cyclization-Homo-Michael” Reactions of 1,3-Bissilyl Enol Ethers with 1,1-Diacylcyclopropanes

Abstract

The Lewis acid mediated domino "[3+3]-cyclization-homo-Michael" reaction of 1,3-bissilyl enol ethers with 1,1-diacylcyclopropanes allows an efficient one-pot synthesis of functionalized salicylates containing a halogenated side chain. A great variety of substitution patterns could be realized by variation of the starting materials and of the Lewis acid. The mechanism of the domino process was studied.