Concepedia

Reductively activated disulfide prodrugs of paclitaxel

Vivekananda M. Vrudhula, John F. MacMaster, Zhengong Li, David E. Kerr, Peter D. Senter

Bioorganic & Medicinal Chemistry Letters · 2002 · 90 citations · 9 references

DOI

Concepts

References

9

Stereochemistry of carbon compounds

Journal of the Franklin Institute · 1962 · 1.1K citations

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Mitomycins and Porfiromycin: Chemical Mechanism of Activation and Cross-linking of DNA

V. N. Iyer, Waclaw Szybalski · Science · 1964 · 569 citations

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Captopril inhibits angiogenesis and slows the growth of experimental tumors in rats.

Olga V. Volpert, William F. Ward, Mark W. Lingen et al. · Journal of Clinical Investigation · 1996 · 332 citations · Full text

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Modified Taxols, 6. Preparation of Water-Soluble Prodrugs of Taxol

Zhiyang Zhao, David G. I. Kingston, Alfred R. Crosswell · Journal of Natural Products · 1991 · 70 citations

, , +6

Synthesis of novel paclitaxel prodrugs designed for bioreductive activation in hypoxic tumour tissue

Eric W. P. Damen, Tapio Nevalainen, Toine J. M. van den Bergh et al. · Bioorganic & Medicinal Chemistry · 2002 · 62 citations

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